Glutathione, Antioxidant and Cellular Support for Healthy Aging, Detoxification and Immune Wellness

Support your body’s natural antioxidant defenses with Pure Encapsulations NAC + Glycine Powder, a targeted combination of two amino acids needed for the production of glutathione.

Each natural peach-ginger-flavored scoop provides 1.8 grams of N-acetyl-L-cysteine and 1.8 grams of glycine. Together, these nutrients supply cysteine and glycine, two essential building blocks the body uses to produce glutathione—one of its most important internally generated antioxidants.

Glutathione helps protect cells from oxidative stress, supports normal detoxification pathways and contributes to immune, respiratory and mitochondrial health. Maintaining glutathione production becomes increasingly important during periods of physical stress and throughout healthy aging.

NAC + Glycine Powder is an excellent choice for adults focused on cellular resilience, antioxidant protection, healthy aging, respiratory wellness and a balanced nighttime routine.

Benefits of NAC + Glycine

NAC + Glycine Powder supports:

• Natural glutathione production

• Cellular antioxidant defenses

• Protection from oxidative stress

• The body’s natural detoxification pathways

• Liver and cellular wellness

• Immune-system function

• Respiratory health and normal mucus clearance

• Mitochondrial and metabolic function

• Healthy cellular energy production

• Nervous-system balance

• A healthy nighttime wellness routine

• Long-term resilience and healthy aging

1.8 Grams Each of NAC and Glycine

Each scoop provides:

• N-acetyl-L-cysteine — 1,800 mg

• Glycine — 1,800 mg

This balanced combination supplies two amino acids involved in glutathione synthesis.

NAC serves as a stable source of cysteine, while glycine provides another required component of the glutathione molecule. Providing them together supports the body’s ability to produce glutathione within its own cells.

What Is Glutathione?

Glutathione is a small molecule made from three amino acids:

• Cysteine

• Glycine

• Glutamate

It is produced throughout the body and is found in virtually every cell. Glutathione helps neutralize free radicals, recycle other antioxidants and support normal cellular detoxification.

Glutathione is especially important within tissues that face high metabolic or environmental demands, including the liver, lungs, immune cells and mitochondria.

Glutathione production depends on the availability of its amino-acid building blocks. Cysteine can be a limiting factor, while glycine availability may also become less optimal with age or during periods of increased demand.

NAC + Glycine Powder supplies both nutrients in a convenient daily formula.

NAC for Glutathione and Antioxidant Support

N-acetyl-L-cysteine, commonly abbreviated as NAC, is a modified form of the amino acid cysteine.

Cysteine contains sulfur and is required for glutathione production. NAC is widely used in nutritional formulas because it provides a stable and effective way to increase cysteine availability.

NAC supports:

• Glutathione synthesis

• Cellular antioxidant activity

• Normal detoxification

• Respiratory wellness

• Immune defenses

• Mitochondrial protection

• Healthy cellular signaling

NAC also has direct antioxidant properties and helps the body manage reactive compounds generated through normal metabolism, exercise and environmental exposure.

Glycine for Glutathione and Cellular Health

Glycine is a conditionally essential amino acid involved in numerous biological processes.

In addition to serving as a building block for glutathione, glycine contributes to:

• Collagen formation

• Protein synthesis

• Nervous-system signaling

• Creatine production

• Heme production

• Healthy methylation balance

• Cellular repair

• Normal liver function

Glycine also functions as an inhibitory neurotransmitter, helping support balanced nervous-system activity.

The body can produce glycine, but internally produced and dietary amounts may not always fully meet demand—particularly during aging, physical stress or periods of increased tissue repair.

NAC and Glycine Work Better Together

Taking NAC alone provides cysteine, but glutathione production also requires adequate glycine.

Combining NAC and glycine provides two of the three amino acids used to make glutathione. The third, glutamate, is generally more widely available within the body.

This complementary approach supports:

• Intracellular glutathione production

• A healthy balance between reduced and oxidized glutathione

• Cellular antioxidant capacity

• Mitochondrial function

• Protection from excessive oxidative stress

The NAC and glycine combination is often referred to as GlyNAC in healthy-aging research.

NAC + Glycine and Healthy Aging

Oxidative stress occurs when reactive compounds exceed the body’s ability to neutralize them effectively.

Normal metabolism, environmental exposure, intense exercise, inadequate sleep and aging can all increase oxidative demands. At the same time, glutathione production and antioxidant capacity may become less efficient over time.

NAC + Glycine Powder supports a longevity-focused routine by helping maintain:

• Glutathione production

• Cellular antioxidant defenses

• Mitochondrial function

• Metabolic health

• Immune resilience

• Physical function

• Healthy tissue maintenance

• Protection from age-related oxidative stress

The combination has been studied for its potential role in healthy aging, but research formulations and dosages vary. NAC + Glycine should be viewed as nutritional support rather than a treatment for aging or age-related disease.

Mitochondrial and Cellular-Energy Support

Mitochondria help convert nutrients into usable cellular energy. This process naturally generates reactive compounds that must be managed by antioxidant systems.

Glutathione helps protect mitochondria and other cellular structures from excessive oxidative stress. NAC and glycine also participate in broader pathways related to metabolism, cellular repair and energy regulation.

NAC + Glycine Powder can complement other mitochondrial and cellular-energy supplements such as:

• Ubiquinol-QH

• Creatine monohydrate

• Magnesium Glycinate

• O.N.E. Multivitamin

• O.N.E. Omega

These supplements work through different biological pathways and should be selected according to individual goals, diet and health status.

Natural Detoxification Support

The body is continuously processing and eliminating metabolic byproducts and environmental compounds through the liver, kidneys, digestive system, lungs and skin.

Glutathione plays an important role in several phases of normal liver detoxification. It helps bind and transform certain compounds so they can be processed and eliminated more effectively.

NAC + Glycine Powder supports the body’s existing detoxification systems by promoting glutathione production.

This is different from a restrictive “detox cleanse.” Supporting detoxification should focus on:

• Adequate protein and amino acids

• Fiber-rich foods

• Consistent hydration

• Regular bowel movements

• Limited alcohol exposure

• Nutrient-dense meals

• Healthy liver and kidney function

• Reduced exposure to tobacco and unnecessary toxins

NAC + Glycine does not remove all toxins or replace medical treatment for poisoning, liver disease or toxic exposure.

Liver and Cellular Wellness

The liver uses glutathione extensively to manage oxidative stress and support normal detoxification pathways.

NAC provides cysteine needed for glutathione production, while glycine supplies another essential component. Together, they offer nutritional support for normal liver and cellular function.

Customers with diagnosed liver disease, abnormal liver tests or a history of significant alcohol use should seek professional guidance rather than using supplements as a substitute for evaluation or treatment.

Respiratory Wellness

NAC has a natural affinity for respiratory tissues and supports normal mucus consistency and clearance.

Its sulfur-containing structure can help maintain the physical properties of mucus, while its role in glutathione production supports antioxidant defenses within respiratory tissues.

NAC + Glycine may support:

• Normal respiratory function

• Healthy lung-tissue antioxidant defenses

• Normal mucus clearance

• Immune defenses within the respiratory tract

• Healthy epithelial and ciliary function

It is not intended to treat asthma, chronic obstructive pulmonary disease, respiratory infection or another lung condition.

Persistent coughing, wheezing, shortness of breath or chest discomfort requires medical evaluation.

Immune-System Support

Immune cells require effective antioxidant protection during periods of activation and increased metabolic demand.

Glutathione contributes to normal immune-cell function and helps protect tissues from excessive oxidative stress. NAC also supports the health of epithelial barriers within the respiratory tract.

NAC + Glycine Powder can complement an immune-support routine that includes:

• Adequate sleep

• Balanced nutrition

• Sufficient dietary protein

• Regular physical activity

• Vitamin D

• Appropriate zinc intake

• Stress management

• Recommended preventive healthcare

It is not a treatment for viral, bacterial or other infections.

Glycine for Stress and Nighttime Wellness

Glycine participates in inhibitory nervous-system signaling and can support a calm physiological state.

It is frequently included in nighttime wellness routines because it may help support:

• Nervous-system balance

• Relaxation before bed

• Normal sleep regulation

• A healthy nighttime body-temperature rhythm

• Next-day mental freshness

Each serving of NAC + Glycine Powder contains 1.8 grams of glycine. Some sleep studies have used different or higher amounts, so this product should not be represented as a dedicated sleep medication or guaranteed sleep solution.

Its primary role remains glutathione and healthy-aging support, with nighttime wellness serving as a valuable secondary benefit.

NAC + Glycine for Stress Resilience

Physical and emotional stress can increase metabolic activity and oxidative demand.

NAC + Glycine does not directly lower cortisol or act as a sedative. Instead, it supports the antioxidant and cellular systems that help the body remain resilient during demanding periods.

It may complement stress-focused products such as Cortisol Calm and Magnesium Glycinate, which provide more direct support for relaxation and a healthy stress response.

Exercise and Recovery Support

Exercise offers major health benefits but also creates temporary oxidative and metabolic stress.

The body normally adapts to this challenge by strengthening its antioxidant and recovery systems. Glutathione contributes to these defenses and helps protect cells during normal energy production.

NAC + Glycine Powder can support an active lifestyle by promoting:

• Cellular antioxidant capacity

• Mitochondrial function

• Recovery from normal physical stress

• Immune resilience

• Healthy tissue maintenance

It should not be used to replace adequate protein, carbohydrates, hydration, sleep or appropriate rest between workouts.

Natural Peach-Ginger Flavor

NAC naturally contains sulfur and can have a distinctive aroma and flavor.

The natural peach-ginger formula combines peach, mango, orange and ginger flavor notes to create a more enjoyable daily drink.

The powder is sweetened with purified stevia leaf extracts and also includes potassium citrate and tri-magnesium citrate.

Product Highlights

• 1.8 grams of NAC per serving

• 1.8 grams of glycine per serving

• Supports natural glutathione synthesis

• Supports antioxidant defenses

• Supports healthy aging and cellular resilience

• Supports normal detoxification pathways

• Supports immune and respiratory wellness

• Supports mitochondrial and metabolic function

• Glycine supports nervous-system balance

• Natural peach-ginger flavor

• Approximately 30 servings per container

• 5.6 oz., or 159 grams, per container

• Vegan and vegetarian

• Gluten-free

• GMO-free

• Free from artificial colors and sweeteners

• Free from unnecessary binders, fillers and preservatives

• Synthetically derived NAC and glycine

Ingredients

Each approximately 5.3-gram scoop provides:

• N-acetyl-L-cysteine — 1,800 mg

• Glycine — 1,800 mg

Other ingredients include natural peach, mango, orange and ginger flavors with other natural flavors, potassium citrate, tri-magnesium citrate and purified stevia leaf extracts.

Suggested Use

Mix one scoop daily with 8 ounces of water and take between meals.

Stir or shake thoroughly until the powder is dissolved.

Daily consistency is generally more important than taking it at one exact time. Some customers prefer the morning or afternoon, while others use it as part of an evening wellness routine.

Follow individualized instructions when provided by a qualified healthcare professional.

Frequently Asked Questions

What is Pure Encapsulations NAC + Glycine Powder?

NAC + Glycine Powder is a peach-ginger-flavored amino-acid supplement providing equal amounts of N-acetyl-L-cysteine and glycine.

The combination supports glutathione production, cellular antioxidant defenses, normal detoxification, immune wellness, respiratory health and healthy aging.

How much NAC is in each serving?

Each scoop provides 1,800 mg, or 1.8 grams, of N-acetyl-L-cysteine.

How much glycine is in each serving?

Each scoop provides 1,800 mg, or 1.8 grams, of glycine.

What is the serving size?

One serving is approximately one 5.3-gram scoop.

How many servings are in each container?

Each 5.6-ounce container provides approximately 30 servings.

What flavor is NAC + Glycine Powder?

It has a natural peach-ginger flavor with additional mango and orange flavor notes.

What is GlyNAC?

GlyNAC is a commonly used term for the combination of glycine and N-acetyl-L-cysteine.

NAC supplies cysteine, while glycine supplies another amino acid required for glutathione production.

Is this product considered GlyNAC?

Yes. It provides NAC and glycine together and can be described as a GlyNAC formula.

However, clinical studies may use different amounts or weight-based dosing, so the product should not be assumed to reproduce every outcome from GlyNAC research.

What does glutathione do?

Glutathione is an antioxidant produced within the body. It helps protect cells from oxidative stress, recycles other antioxidants and supports normal detoxification, immune function and cellular health.

Why combine NAC and glycine?

Glutathione is made from cysteine, glycine and glutamate.

NAC supplies cysteine, while glycine supplies a second necessary building block. Providing both nutrients together supports the body’s ability to produce glutathione.

Is NAC the same as glutathione?

No.

NAC is a source of cysteine that the body can use to make glutathione. It supports internal glutathione production rather than supplying the same compound directly.

Is glycine the same as collagen?

No.

Glycine is an individual amino acid and is one of the major amino acids found in collagen. Collagen peptides contain glycine along with proline, hydroxyproline and other amino acids.

What does NAC support?

NAC supports:

• Glutathione production

• Cellular antioxidant defenses

• Respiratory wellness

• Normal mucus clearance

• Immune defenses

• Natural detoxification

• Mitochondrial protection

What does glycine support?

Glycine supports:

• Glutathione production

• Nervous-system signaling

• Collagen formation

• Creatine synthesis

• Healthy methylation balance

• Cellular repair

• Nighttime wellness

Does NAC + Glycine support healthy aging?

Yes. It supports glutathione production, mitochondrial health and protection from oxidative stress—important components of a comprehensive healthy-aging routine.

It does not stop aging or treat age-related diseases.

Does NAC + Glycine support detoxification?

Yes. Glutathione plays an important role in normal liver and cellular detoxification pathways.

NAC + Glycine supports these natural processes but is not a cleanse or treatment for toxic exposure.

Does NAC + Glycine support liver health?

The ingredients support glutathione production and normal cellular detoxification, both of which are important to liver wellness.

Customers with liver disease or abnormal liver tests should consult their healthcare professional before use.

Does NAC support respiratory health?

Yes. NAC supports respiratory antioxidant defenses, normal mucus consistency and healthy clearance mechanisms.

It is not intended to treat asthma, pneumonia, chronic obstructive pulmonary disease or another respiratory condition.

Does NAC loosen mucus?

NAC’s sulfur-containing structure can support normal mucus consistency and clearance.

Persistent congestion, coughing, wheezing or difficulty breathing should be medically evaluated.

Does NAC + Glycine support immune health?

Yes. Glutathione contributes to normal immune-cell function, while NAC supports antioxidant defenses and respiratory epithelial health.

Can NAC + Glycine help with sleep?

Glycine supports inhibitory nervous-system signaling and may complement a healthy nighttime routine.

The product is not a sedative or sleep medication, and results vary. Persistent insomnia requires appropriate evaluation.

Should I take NAC + Glycine before bed?

It may be taken in the evening between meals, especially when incorporating glycine into a nighttime routine.

Some customers prefer taking NAC earlier in the day. Choose a consistent time that fits your routine and individual response.

Does NAC + Glycine lower cortisol?

It is not formulated to directly lower cortisol.

Its stress-related benefits are associated primarily with antioxidant support, cellular resilience and glycine’s role in nervous-system regulation.

Does NAC + Glycine help with anxiety?

The formula supports nervous-system and antioxidant health but is not intended to treat anxiety disorders.

Persistent anxiety, panic attacks or significant mood changes should be discussed with a qualified healthcare or mental-health professional.

How do I take NAC + Glycine Powder?

Mix one scoop into approximately 8 ounces of water and consume it between meals.

Why should NAC + Glycine be taken between meals?

Amino-acid supplements are often taken between meals to reduce competition with other dietary amino acids and support consistent use.

Customers who experience stomach discomfort may need individualized guidance about timing.

Can I take NAC + Glycine with food?

The suggested use is between meals.

Taking NAC with food may improve digestive comfort for some users, but follow professional guidance before changing the recommended use.

Can I take NAC + Glycine every day?

Yes. It is formulated for daily supplementation when appropriate for the individual.

Long-term use should be reviewed with a healthcare professional when medications or health conditions are involved.

How long does NAC + Glycine take to work?

NAC + Glycine is nutritional support rather than a fast-acting stimulant.

Changes depend on baseline nutrient status, age, diet, oxidative demands, serving consistency and the outcome being assessed.

Does NAC + Glycine provide immediate energy?

No. It does not contain caffeine or stimulants.

It supports mitochondrial and cellular health rather than producing an immediate energy surge.

Does NAC + Glycine contain caffeine?

No caffeine is listed in the formula.

Can I take NAC + Glycine with O.N.E. Multivitamin?

Yes. O.N.E. Multivitamin provides foundational vitamins, minerals and antioxidants, while NAC + Glycine supplies targeted amino-acid support for glutathione production.

Can I take it with Magnesium Glycinate?

Yes. The products can complement one another within a healthy-aging, stress and nighttime-wellness routine.

The NAC + Glycine formula contains tri-magnesium citrate as an additional ingredient, but the amount of elemental magnesium is not presented as a meaningful supplemental serving.

Can I take NAC + Glycine with Cortisol Calm?

Yes, when appropriate.

Cortisol Calm provides targeted adaptogenic and relaxation support, while NAC + Glycine focuses primarily on glutathione, cellular resilience and antioxidant protection.

Can I take NAC + Glycine with O.N.E. Omega?

Yes. Omega-3 fatty acids and GlyNAC support different aspects of cellular, cardiovascular and healthy-aging wellness.

Can I take NAC + Glycine with Ubiquinol-QH?

Yes. Ubiquinol supports mitochondrial energy and antioxidant activity, while NAC + Glycine supports glutathione production.

Can I take NAC + Glycine with creatine?

Yes. Glycine participates in the body’s natural creatine synthesis, while supplemental creatine provides direct support for cellular energy, strength and exercise performance.

Can I take NAC + Glycine with collagen?

Yes. Glycine is an important component of collagen, while collagen peptides provide a broader range of collagen-specific amino acids.

The two products serve related but distinct nutritional purposes.

Can I take NAC + Glycine with Berberine UltraSorb?

They may be used within the same metabolic and healthy-aging routine.

Customers taking prescription medication or managing blood-glucose concerns should review their complete supplement program professionally.

Can I mix NAC + Glycine into a smoothie?

It can be mixed with a beverage, although the suggested use is one scoop in water between meals.

Combining it with a protein-rich smoothie may reduce the practical benefit of taking the free-form amino acids away from other dietary amino acids.

Can I mix it with electrolytes?

It may be mixed with a compatible electrolyte drink, but combining flavored products can alter the taste.

Review total mineral intake when using several supplements together.

Can I mix it with hot water?

Warm water may be used, but avoid prolonged exposure to excessive heat.

Cool or room-temperature water generally provides the simplest preparation and best flavor.

Why does NAC have a sulfur smell?

NAC contains sulfur and may naturally produce an odor similar to sulfur or cooked eggs.

This does not necessarily mean the product has spoiled. The natural peach-ginger flavor helps make the powder more enjoyable.

Is NAC the same as a sulfa drug?

No. NAC is not a sulfonamide antibiotic.

A sulfa-drug allergy does not automatically mean someone is allergic to NAC, although anyone with a history of serious medication reactions should consult a healthcare professional before use.

Is NAC + Glycine vegan?

Yes. Both NAC and glycine are synthetically derived, and the formula uses vegan ingredients.

Is it vegetarian?

Yes. It is suitable for vegetarian diets.

Is NAC + Glycine gluten-free?

Yes. It is gluten-free.

Is it non-GMO?

Yes. It is GMO-free.

Does it contain artificial sweeteners?

It contains purified stevia leaf extracts rather than artificial sweeteners.

Does it contain sugar?

Sugar is not listed among the ingredients.

Customers following a medically prescribed diet should review the current physical label for complete information.

Can NAC cause digestive discomfort?

NAC may cause:

• Nausea

• Stomach discomfort

• Heartburn

• Diarrhea

• Gas

• Headache

Taking only the recommended serving and mixing it thoroughly may improve tolerance.

Can glycine cause digestive discomfort?

Large amounts of glycine may cause nausea, soft stools or stomach discomfort in some individuals.

Discontinue use and seek guidance if significant symptoms occur.

Can NAC interact with nitroglycerin?

NAC may enhance the blood-vessel-relaxing effects of nitroglycerin and increase the likelihood of headache, dizziness or low blood pressure.

Customers taking nitroglycerin or another nitrate medication should consult their prescriber before use.

Can NAC + Glycine be taken with blood thinners?

NAC may influence platelet activity in some circumstances.

Customers using anticoagulant or antiplatelet medication should consult their prescriber or pharmacist before use.

Can NAC be taken during cancer treatment?

Antioxidant supplements may interact with certain chemotherapy or radiation treatments.

Customers undergoing cancer treatment should obtain approval from their oncology team before using NAC + Glycine.

Can people with asthma take NAC?

People with asthma or reactive airway conditions should consult a healthcare professional before using NAC, particularly when respiratory symptoms are not well controlled.

Can pregnant customers take NAC + Glycine?

Pregnant customers should consult their healthcare professional before use.

Can nursing customers take NAC + Glycine?

Breastfeeding customers should consult their healthcare professional before using NAC + Glycine.

Can children take NAC + Glycine Powder?

The product is intended for adults ages 18 and older.

A pediatrician should determine whether NAC, glycine or another supplement is appropriate for a child or teenager.

Who should consult a healthcare professional before use?

Professional guidance is particularly important for customers who:

• Are pregnant or nursing

• Take prescription medication

• Use nitroglycerin or nitrate medication

• Take anticoagulant or antiplatelet medication

• Have asthma or another respiratory condition

• Have liver or kidney disease

• Are undergoing cancer treatment

• Have an upcoming surgical procedure

• Have a diagnosed medical condition

• Are under 18 years old

Should NAC + Glycine be stopped before surgery?

Tell the surgical team about every supplement and medication being used.

Follow its instructions regarding when to discontinue NAC + Glycine before a procedure.

How should NAC + Glycine Powder be stored?

Store the container tightly closed in a cool, dry place away from heat, moisture and direct sunlight.

Use a clean, dry scoop and keep the product out of reach of children.